Harvard Medical School

The Harvard Medical School is developing a next generation protein array that combines Lumera's ExpressTag™ protein immobilization technology with Harvard’s NAPPA™ methodology, a protein microarray technology that allows for the in situ synthesis of entire proteomes on demand. The resultant high density protein arrays will be used with the PlexArray™ System to simultaneously measure the affinity and kinetics of hundreds of protein-protein interactions. The technology developed in this project will be a valuable tool for understanding protein function and is expected to significantly increase the speed of drug discovery and life science research.

About Harvard Institute for Proteomics

Under the direction of Joshua LaBaer, M.D., Ph.D., the Harvard Institute of Proteomics has taken the next step beyond the Human Genome Project, by cloning all available human genes in a standard form, enabling full-length, high throughput protein expression. To study proteins, biologists first need to capture the genes encoding them, then move those genes into an appropriate context for experimental analysis. By developing and applying new resources and technologies, HIP enables the study of proteins on a genome-wide scale using informatics and automation. The Institute has produced over fifteen thousand clones to date.