PLEXERA®

ON-CHIP SPRi PLATFORM

KINETIC DATA AT AI SCALE.

An automated wet lab on a single chip.

Your AI designs proteins. We deliver the experimental ground truth in 10–14 days.

Plexera NanoCapture chip connecting an automated wet lab with high-density SPR kinetic measurements
PATENTED NANOCAPTURE3,840–10,000 spots / chip10,000 SPOTS / COMING SOON
10–14 days

From sequence to validation

$69 / ligand

Sequence to protein expression

$10 / interaction

Full affinity · 3 replicates · 8-point concentration series

KD + kon + koff

Binding strength and kinetics

HOW PLEXERA WORKS

From sequence to kinetic truth.

Submit your designs. Plexera runs the complete wet-lab workflow and returns binding kinetics in 10–14 days.

  1. 001

    Share your sequences

    Send protein sequences, target information and the validation goals that matter to your program.

  2. 002

    Express & prepare

    We handle cell-free expression, purification and preparation of the NanoCapture chip.

  3. 003

    Measure on-chip

    3replicates8point concentration series

    Measured in parallel by SPRi.

  4. 004

    Receive kinetic data

    Get complete sensorgrams, KD, kon, koff and a structured experimental report.

ESTIMATE YOUR EXPERIMENT

Build a working budget.

Enter the number of ligand proteins immobilized on the chip and analyte proteins introduced in flow.

Protein expression100 × $69$6,900
Binding interactionsLigand × analyte pairs200
Binding data200 × $10$2,000
Estimated totalWorking estimate in USD$8,900

This estimate excludes the expression, purification and sourcing cost of flow-phase analyte proteins.

Need a confirmed quote? Contact Plexera

A NEW EXPERIMENTAL ARCHITECTURE

Everyone else is automating the lab.
We put the lab on a chip.

Automating the lab changes how experiments move. Moving molecular interactions onto a chip changes how many you can measure at once—and what each data point costs.

THE AUTOMATED LAB

Scale the equipment.

Robotics connect instruments and move samples between steps. Capacity scales with more hardware, handling and lab space.

Sample prepLiquid handlingInstrument

Automation around the assay.

THE PLEXERA ON-CHIP PLATFORM

Scale the interactions.

Dense microarrays, proprietary surface chemistry and SPR imaging bring thousands of molecular interactions into one parallel measurement architecture.

ONE CHIP
3,840 assay spots

Parallelization at the assay itself.

Built differently. Delivered as a service.

An ultra-high-throughput on-chip SPRi platform, integrating cell-free expression, microarray printing and label-free kinetic analysis.

ONE PLATFORM / MULTIPLE MOLECULAR CLASSES

One technology platform.
More molecular possibilities.

An ultra-high-throughput on-chip SPRi platform for binding kinetics across diverse molecular formats.

BUILT FOR AI PROTEIN DESIGN

Give your model
more reality.

Predictions need experiments. Plexera generates the wet-lab evidence that connects what your model designs to how a molecule actually binds.

01

Train on measured biology

Build experimental datasets that connect protein sequences with measured molecular interactions.

02

Validate beyond a hit

See how tightly a candidate binds, how quickly it associates and how long the interaction lasts.

03

Close the design loop

Bring experimental feedback into the next round of protein engineering with a 10–14-day cycle.

FULL AFFINITY + KINETICSSPRi
Every interaction tells a story.
Illustrative binding sensorgramConceptual curves show binding response increasing during association and decreasing during dissociation. This is an illustration, not experimental data.AssociationDissociationTimeBinding response

Illustrative sensorgram · not experimental data

KD

How tightly does it bind?

Equilibrium dissociation constant

kon

How quickly does it bind?

Association rate constant

koff

How quickly does it let go?

Dissociation rate constant

FROM IN SILICO TO ON-CHIP

Your next breakthrough
needs real data.

Tell us what you are designing. We will help shape the experiment that moves it forward.

Required fields

Your inquiry will be sent to the Plexera team.

By submitting this form, you agree that Plexera may use the information provided to respond to your inquiry. See our Privacy Policy.